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inventories of species offer especially fertile ground for pharmaceutical companies interested in the potential medicinal value of wild plants.History is replete with drug discoveries from wild plants.In the 1750s, digitalis, used to treat heart failure, was found in the European foxglove plant.In the 1950s, vincristine sulfate, the drug of choice in the treatment of childhood leukemia, was discovered in the Madagascan periwinkle plant.More recently, taxol, approved for treatment of ovarian cancer, was extracted from the Pacific yew, a small tree growing in the Pacific Northwest forests of the United States.These forests are said to contain more than half the world’s estimated 500,000 plant species.Yet fewer than 1 percent have been thoroughly researched for medicinal benefit.One of the firm’s distinctions is its novel approach to drug discovery.Traditional discovery processes rely on the random screening of thousands of plants in the hope of finding a chemical compound with therapeutic value.Ethnobotanists at the firm work with native healers to identify and evaluate the plants they use to treat diseases in their cultures.The active ingredient in the plant then becomes a candidate for further testing and development.Conte and the scientists employed at Shaman believe that this approach can dramatically reduce the costs and improve the odds
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